Endocrine Abstracts

Introduction: ‘Atypia of undetermined significance/follicular lesion of undetermined significance’ (AUS/FLUS) is a heterogeneous diagnostic thyroid fine needle aspiration biopsy (FNAB) category. AUS/FLUS is comprised of cases that cannot be definitively diagnosed as benign, suspicious for/consistent with neoplasm, suspicious for malignancy or malignant. The recommended management strategy for these cases is to perform a repeat FNAB after an appropriate time course. A...

Introduction: Graves’ disease and toxic multinodular goiter are known to have different etiologies and pathogenesis, which are not fully comprehended today. This study compares the protein profiles of Graves’ disease and toxic multinodular goiter patients’ thyroid samples using proteomics methods and investigates the role of differentiating proteins in the pathogenesis of these diseases.Methods and Design: Difference Gel Electrophoresis (D...